Research on the intestinal microbiome is uncovering potential new probiotic species that could revolutionize medicine. The research is also destroying some rather long-held, but limited views on how to influence the composition of the microbiome. The focus in the marketplace has been on attempt to influence the microbiome through supplementation with lactic acid producing bacteria such as Lactobacillus and Bifidobacteria species. The truth is that while these organisms are important they play a rather small and limited role on the microbiome.